Vertex Pharmaceuticals VRTX

equity

Price History

1991-07 · DCA start$4.5

Time underwater

How far below its previous all-time high the price sat, each month. 0% means a new high.

1991-072026-08 · 0.0%

Worst drawdown: −91%, peaking Oct 2000 and bottoming Apr 2004 — 164 months below the prior high before recovering.

DCA Backtest

Start month

Monthly amount (USD)

Invested: $42,200
Value today: $1,041,065
Return: +2367.0%
Months invested: 422

Scenarios

Inflation — the same contributions merely keeping pace with CPI would be $68,906 today, so the real (inflation-adjusted) return is +1410.8%.

Lump sum instead — $42,200 all at once in Jul 1991: $4,930,179 (+11582.9%) — lump sum came out ahead.

Worst timing — same monthly amount started at the all-time high (Apr 2025): $1,977 on $1,700 invested (+16.3%).

⚠ Price returns only — dividends are not included. This understates the true return of dividend-paying shares, and any comparison against crypto (which pays no dividends) is biased against equities by roughly the dividend yield, compounded.

If this saved you a spreadsheet — buy me a coffee.

Every start month at once

Each cell is the return-to-date of £/$/€100-a-month DCA started that month. Click a cell to load it in the backtest above. The ringed cell is the all-time-high start — the worst timing scenario.

	J	F	M	A	M	J	J	A	S	O	N	D
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026

Legend:−50%−20%0%+50%+200%+1000%worst timing (ATH)Selected 1991-07: +2367.0%

About Vertex Pharmaceuticals

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England. (Wikipedia)

It's a listed company categorised under health care and biotechnology, with a market cap of about $133.3B.

It rates High Risk at 3.1/5, meaning several rated factors score badly, so this carries materially more risk than a typical holding.

What pushes the score up: earnings quality (5.0/5) and market / volatility (3.3/5).

Scoring well: liquidity at 1.0/5.

Not yet researched: leverage / financial, concentration, governance. These are excluded from the score rather than guessed, so the real risk may be higher than what’s shown.

Ratings summarise sourced facts against fixed rules — not investment advice, and no substitute for your own diligence.

Risk Profile

High Risk(3.1/5)60% rated

How these ratings work

Market / Volatility3.3/5 · weight 20%

Annualised volatility (3yr)3/526.0
Max drawdown from ATH5/590.7
Beta vs S&P 5002/50.90

Liquidity1.0/5 · weight 15%

Avg daily $ volume1/5735.2m
Float % of shares outstandingnot yet researched

Leverage / Financialunrated · weight 20%

Debt / equitynot yet researched
Interest coverage (EBIT / interest)not yet researched

Earnings Quality5.0/5 · weight 15%

3yr EPS volatility5/5100

Concentrationunrated · weight 10%

Largest customer, % of revenuenot yet researched
Geographic revenue concentrationnot yet researched

Governanceunrated · weight 10%

Board independence %not yet researched
Share structurenot yet researched
Litigation / audit historynot yet researched

Sector / Regulatory3.0/5 · weight 10%

Sector regulatory exposure3/5elevated

Linked Assets

Same sector, or return-correlated — worth knowing what else might move if this one does.